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Colon Cleanse Smoothie: 10 Options In 2024

colon cleanse smoothie
Smoothies have numerous health benefits. Photo: Daniel Hoz/Shutterstock

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You may be on the hunt for the perfect dietary support that can adequately meet your needs as you deal with irritable bowel syndrome or IBS. This would involve fruits and vegetables, as well as other whole foods that provide antioxidant support to cleanse your gastrointestinal tract. Cleaning your system can help you alleviate the symptoms associated with IBS, such as gastrointestinal discomfort, hypersensitivity, and stress.

A colon cleanse smoothie can be a nutritious and efficient answer to these needs. Smoothies and juices that are produced from vegetables, fruits, nuts, and seeds may be what you need to give a nutritive boost to your system. As we continue, we’ll discuss smoothie recipes that consist of detox-promoting nutrients. We will also cover helpful ways to make and drink these smoothies[1] in a way that is most effective for your colon.

10 Colon Cleanse Smoothies

  • Green Giant.
  • Sweet Strawberry Surprise.
  • Creamy Avocado & Berry Breeze.
  • Homemade Pumpkin Spice.
  • Citrus Splendor.
  • Breakfast Blend.
  • Fresh Green Horizons.
  • Banana & Strawberry.
  • Sunshine Splash.

Colon Cleanse Smoothies

For these fun and easy recipes, we can use low-FODMAP foods,[2] i.e. fermentable oligosaccharides, disaccharides, monosaccharides, and polyols, that can help manage IBS. These foods, as well as foods your physician recommends, can be blended into a smoothie. You can use any combination of gastrointestinal-supporting healthy food items and mix them based on the taste and texture you desire.

Green Giant

colon cleanse smoothie
Green smoothies are nutrient-dense. Photo: Alkema Natalia/Shutterstock

A classic way to cleanse your colon is with a green smoothie. Using spinach as a simple foundation can be effective, as this is a low-FODMAP food.


  • Rice milk.
  • Spinach.
  • Pumpkin seeds.

You could put a spin on a savory-style meal and blend it into a savory green smoothie. Start with a cup of rice milk for its neutral flavor, then toss your raw spinach into the blender. You can top this off with pumpkin seeds.

Sweet Strawberry Surprise

If you’re interested in a sweet colon cleanse smoothie recipe, one that includes strawberries, a great antioxidant source, will be your perfect choice. Strawberries are another great low-FODMAP food, so consumption won’t lead to bloating or colonic distention. 


  • Almond milk.
  • Strawberries.
  • Hazelnuts or chia seeds.

Using a cup of almond milk as the base, add your frozen or fresh strawberries and blend for a sweet sensation. Finish it off with chopped hazelnuts to provide great flavor and some texture. If the taste seems too sweet and nutty, you can substitute hazelnuts with chia seeds for a more subtle taste.

Creamy Avocado And Berry Breeze

Try a colon-cleansing smoothie recipe that includes raspberry. Raspberries are made up of phytochemicals, like anthocyanin, that are  beneficial for human health.[3] This includes gut health, in which raspberries support positive shifts in microflora and the gut microbiome.

You may want to pair this with healthy fats like avocado and nuts.[4] The avocado possesses a significant phytonutrient and fiber content. Additionally, avocados increase beneficial bacteria in the colon. 


  • Lactose-free milk.
  • Avocado.
  • Raspberries.
  • Almonds.

All you need is a knife or a slicer to chop your avocado. Add a cup of raspberries and chopped avocado into the blender with your lactose-free milk base. The mixture of avocado and raspberry can make for a creamy and smooth combination. Add some chopped almonds for a contrast in taste and texture.

Green Tea Berry Burst

The great thing about smoothies is that you can be as versatile as you want, and you can even include green tea. This is an advantageous addition to your smoothie because green tea contains polyphenols, such as catechins, that provide antioxidants.[5] This protects cells against damage and modulates inflammation while also fostering a beneficial shift among the gut microbiomes.

You can make a great smoothie to cleanse the colon by adding berries and yogurt as well. Yogurt is a good source of probiotics that nurture beneficial bacteria, and berries are stuffed with antioxidants and phytochemicals like anthocyanin that decrease inflammation.


  • Green tea bags or powder.
  • Greek yogurt.
  • Mixed berries.
  • Vanilla extract.

For this recipe, you can brew two bags of green tea the night before you prepare your smoothie and let it chill overnight until used. An alternative would be to steep the tea for three minutes on smoothie day and add ice cubes for cooling.

Add one cup of Greek yogurt to the blender, followed by one or two cups of your choice of mixed berries: strawberries, blueberries, or even blackberries. If you opt for green tea powder instead, add the powder and finish it off with a dash of vanilla for flavor.

Homemade Pumpkin Spice

We all love a good pumpkin spice latte during the holiday season, so you could try a pumpkin spice smoothie. Pumpkin makes a great ingredient for colon-cleansing smoothies because the flesh, peel, and seeds are filled with fiber and antioxidants.[6] They also contain minerals like zinc, iron, and calcium.

The anti-microbial and anti-ulcer capabilities of pumpkin, paired with its anti-inflammatory characteristics, make pumpkin very effective in supporting digestive health.

Spices like cinnamon and nutmeg are a great addition to this smoothie because of their health benefits.[7] The active compounds in these spices can serve as health biomarkers.

Cinnamon contains the anti-inflammatory cinnamaldehyde compound. Nutmeg possesses myristicin, which has stomach-soothing and stress-relief properties that can help cleanse the colon and alleviate any GI discomfort.


  • Pumpkin.
  • Greek yogurt.
  • Almond milk.
  • Cinnamon.
  • Nutmeg.
  • Almond butter.
  • Vanilla extract.

Get one or two small pumpkins and wash them before cutting them into halves. After this, it is  easy to separate from the stem so you can scoop out your seeds and salt your pumpkin halves, then roast them until the flesh softens. After roasting, blend the flesh to make your pumpkin puree.

Get a cup of Greek yogurt and almond milk to give it a creamy and soft texture, then add your pumpkin puree to this liquid base. You can also add cinnamon, nutmeg, and almond butter. Finish this off with a little vanilla extract and a teaspoon of maple syrup if you like.

Citrus Splendor

Citrus fruits are a great addition to detox smoothies because of their antioxidative and anti-inflammatory effects. The flavanone constituents of citrus fruit support the balance of intestinal homeostasis[8] within the gut. This can work to cleanse the colon and optimize your GI health.


  • Greek yogurt.
  • Almond milk.
  • One zested lemon.
  • Two peeled oranges.
  • Sliced kiwi.
  • Flax seeds.

Take your grater and zest the lemon until the peel is removed.  Add your almond milk and Greek yogurt to the blender. Next, add your oranges and lemon and blend the mixture.

You can include a kiwi or another fruit of your choice, like pineapple or mango, to provide some sweetness to this zesty treat. Also, consider adding flax seeds for the fiber and omega-3 content.

Breakfast Blend

colon cleanse smoothie
Smoothies can help alleviate abdominal pain and bloating. Photo: hannahby/Shutterstock

You can build your diet up with colon cleanse smoothie recipes that include oats and berries, as these are low-FODMAP foods. You’ll be able to alleviate any abdominal pain or bloating as well as bowel irregularities that are associated with IBS.


  • Coconut milk.
  • Greek yogurt.
  • Oats.
  • Blueberries.
  • Vanilla extract.

Based on your preference, you can either add the cooked or uncooked oats. Start with your coconut milk and Greek yogurt. Add your oats and blueberries to the mixture, as well as vanilla extract, and blend. If you like, you can finish this off with chopped almonds.

Fresh Green Horizons

This drink is a great-tasting and effective green detox smoothie that consists of chlorophyll-containing foods that exhibit healthy antioxidant and anti-inflammatory[9] characteristics. The vibrant color of these foods reflects the nutrients that are packed within them.


  • Plain non-fat yogurt.
  • Spinach.
  • Cucumber.
  • Green bell pepper.
  • Lemon.

Starting with yogurt, add spinach, cucumber, and green bell pepper to your mixture and blend. Add lemon zest to give a flavor boost. Additionally, you can include green grapes if you like a sweeter taste.

Banana And Strawberry

You can make simple, healthy smoothie recipes from the whole foods in your pantry that you’d use for breakfast, lunch, or dinner. The fiber and nutrient content can foster a positive balance within your colon. 


  • Greek yogurt.
  • Almond milk.
  • Strawberries.
  • Bananas.
  • Crushed nuts.

Add strawberry and banana slices to your Greek yogurt and almond milk. You can add vanilla and crushed nuts for added flavor and texture.

Sunshine Splash

If the season is right, you can enjoy these vibrant fruits as they can support IBS management and work towards healing the gut.


  • Greek yogurt.
  • Orange juice.
  • Cantaloupe.
  • Mango.

Blend your Greek yogurt and orange juice in with the diced cantaloupe and mango. You can use fresh or frozen fruit based on your preference. Also, you can include a choice of milk if you want to alter the flavor and texture.

Tips For Making And Drinking Smoothies

Greek Yogurt

In many of your smoothies, you’ll want to include Greek yogurt, as this is a great source of probiotics.[10] Greek yogurt helps optimize the beneficial bacteria within the gut, allowing for more efficient function. It provides protein that helps satiety and is a great way to thicken a smoothie.

Consider The Contents

Maximize the bioactive compounds[11] included in the smoothie by using the seeds and peels that usually become waste products. Also, putting the liquids in first and then any powders and food components will help you achieve a smoother consistency.

Coordinated Timing

A  healthy meal pattern is essential for getting your gut back on track. Having your detox smoothies in the morning or as a snack between meals can provide digestive support and energy boosts. 


To cleanse your colon and manage your IBS, you can make a smoothie or a green juice that will nurture your immune system while alleviating any inflammation and toxicities within your system. This can help clean your gut and reset your colon for adequate function.

Additionally, following a low-FODMAP diet can provide the necessary relief that you may need from uncomfortable symptoms. Abdominal cramps, bloating, or constipation can be resolved. It’s also important to note that this dietary pattern can create advantageous gut microbiota shifts, optimizing total health.

Frequently Asked Questions

What is the best smoothie for a colon cleanse?

To make the best smoothie for a colon cleanse, you must incorporate foods that promote positive effects on the colon and gastrointestinal health. These include antioxidants, protein, and fiber to bolster satiety, bowel function, and detoxification.

What is the best fruit to detox the colon?

Citrus fruits may be the best fruit to detox the colon. Fruit such as lemons, oranges, and limes contain vitamin C, which is vital for detox.

Can you really cleanse your colon?

Yes. Aside from physical cleansing protocols, dietary interventions have an essential role in cleansing the colon. Eating the appropriate amount of fiber and protein while steering clear of fermentable foods can help. You can also use a digestive health supplement.

How do you know if you need a colon cleanse?

If you experience symptoms such as IBS gas and abdominal pain, to name a few, you may need a closer diagnosis. The presence of IBS complications is often a telltale sign that you may need to cleanse your colon.

+ 11 Sources

EHproject has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We work mostly with peer-reviewed studies to ensure accurate information. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

  1. Lietzow, J., Sachse, B. and Bernd Schäfer (2022). Drinking your Greens: Green Smoothies from a Nutritional and Toxicological Point of View. [online] ResearchGate. Available at: https://www.researchgate.net/publication/365835829_Drinking_your_Greens_Green_Smoothies_from_a_Nutritional_and_Toxicological_Point_of_View.
  2. Adelina Nicoleta Galica, Galica, R. and Dumitrașcu, D.L. (2022). Diet, fibers, and probiotics for irritable bowel syndrome. Journal of medicine and life, [online] 15(2), pp.174–179. doi:https://doi.org/10.25122/jml-2022-0028.
  3. Zhang, S., Xu, M., Sun, X., Liu, X., Fouad Choueiry, Xu, R., Shi, H. and Zhu, J. (2022). Black raspberry extract shifted gut microbe diversity and their metabolic landscape in a human colonic model. Journal of Chromatography B, [online] 1188, pp.123027–123027. doi:https://doi.org/10.1016/j.jchromb.2021.123027.
  4. Dreher, M.L., Cheng, F.W. and Ford, N.B. (2021). A Comprehensive Review of Hass Avocado Clinical Trials, Observational Studies, and Biological Mechanisms. Nutrients, [online] 13(12), pp.4376–4376. doi:https://doi.org/10.3390/nu13124376.
  5. Xu, M., Yang, K. and Zhu, J. (2020). Monitoring the Diversity and Metabolic Shift of Gut Microbes during Green Tea Feeding in an In Vitro Human Colonic Model. Molecules, [online] 25(21), pp.5101–5101. doi:https://doi.org/10.3390/molecules25215101.
  6. Hussain, A., Kausar, T., Sawera Sehar, Sarwar, A., Abdul Haseeb Ashraf, Jamil, M., Noreen, S., Rafique, A., Iftikhar, K., Muhammad Yousaf Quddoos, Aslam, J. and Muhammad Abid Majeed (2022). A Comprehensive review of functional ingredients, especially bioactive compounds present in pumpkin peel, flesh and seeds, and their health benefits. Food Chemistry Advances, [online] 1, pp.100067–100067. doi:https://doi.org/10.1016/j.focha.2022.100067.
  7. Vázquez-Fresno, R., Remus, A., Tanvir Sajed, Tuviere Onookome-Okome, Wishart, N.A. and Wishart, D.S. (2019). Herbs and Spices- Biomarkers of Intake Based on Human Intervention Studies – A Systematic Review. Genes and Nutrition, [online] 14(1). doi:https://doi.org/10.1186/s12263-019-0636-8.
  8. Stevens, Y., Evelien Van Rymenant, Grootaert, C., John Van Camp, Possemiers, S., A.A.M. Masclee and Jonkers, D. (2019). The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health. Nutrients, [online] 11(7), pp.1464–1464. doi:https://doi.org/10.3390/nu11071464.
  9. Martins, T., Barros, A., Rosa, E. and Antunes, L. (2023). Enhancing Health Benefits through Chlorophylls and Chlorophyll-Rich Agro-Food: A Comprehensive Review. Molecules, [online] 28(14), pp.5344–5344. doi:https://doi.org/10.3390/molecules28145344.
  10. Lisko, D.J., G. Patricia Johnston and Johnston, C.G. (2017). Effects of Dietary Yogurt on the Healthy Human Gastrointestinal (GI) Microbiome. Microorganisms, [online] 5(1), pp.6–6. doi:https://doi.org/10.3390/microorganisms5010006.
  11. Marcin Kidoń and Pascaline Aimee Uwineza (2022). New Smoothie Products Based on Pumpkin, Banana, and Purple Carrot as a Source of Bioactive Compounds. Molecules, [online] 27(10), pp.3049–3049. doi:https://doi.org/10.3390/molecules27103049.


Christine is a certified personal trainer and nutritionist with an undergraduate degree from Missouri State University. Her passion is helping others learn how strong and healthy they can become by transforming their daily habits. Christine spends… See More