Best Weight Loss Supplements For Women Over 50 – 8 Most Popular Supplements In 2023

best weight loss supplements for women over 50
You can use weight loss supplements for women over 50. Photo: Team Design

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best weight loss supplements for women over 50
You can use weight loss supplements for women over 50. Photo: Team Design

Have you ever wondered why losing weight gets harder as you get older? Studies[1] show that many women start to gain weight more easily and lose weight more slowly as they age. This is due to several factors, including hormonal changes during menopause transition, a decline in muscle mass, and a slower metabolism.

But don’t worry; there are things you can do to lose weight and improve your overall health, even as you age. On top of a healthy diet and regular exercise, taking the best weight loss supplements for women over 50 can help you reduce belly fat and achieve your weight loss goals safely.

Here, we’ll review the eight best diet pills for women over 50 in 2023. Join us as we explore the benefits of each, potential side effects, tips, and more.

Best Weight Loss Supplements For Women Over 50 In 2023

Are Weight Loss Pills For Women Over 50 Actually Effective?

Whether or not weight loss pills for women over 50 are effective depends on a variety of factors, including the individual’s overall health, lifestyle, and the specific supplement being used. However, some evidence suggests that certain diet pills[2] help promote weight loss.

Some supplements suppress appetite, others boost metabolism, while a couple enhances fat burning. Current research[3] recommends a holistic approach to managing weight, including a balanced diet and regular physical activity outside supplement intake.

8 Best Weight Loss Supplements For Women Over 50 In 2023


  • Unique weight loss formula.
  • Made from scientifically-backed ingredients.
  • May promote weight loss in multiple ways.
  • May boost metabolism.
  • May curb cravings.
  • Limited stock. You can only buy a maximum of five bottles.
  • Expensive.
  • Contains patented blends.

PhenQ, our top-rated fat burner for women, brings together a compelling blend of natural ingredients that support a holistic approach to weight management. Priced at $69.99, it contains the following powerful elements that help you to lose fat:

  • α-Lacys Reset: A trademarked blend of ingredients, including alpha lipoic acid, cysteine, and magnesium, which are known to promote[4] weight loss via appetite suppression.[5]
  • Capsimax powder: Rich in capsaicinoids,[6] it enhances thermogenesis, hindering fat cell accumulation.
  • Chromium picolinate: Curbs cravings,[7] further reducing cravings for unhealthy foods.
  • Caffeine: Caffeine[8] boosts alertness, reduces fatigue, and aids fat burning.
  • Nopal cactus: High in fiber, Nopal cactus can reduce[9] triglycerides and glucose levels, promoting a feeling of fullness.
  • L-carnitine fumarate: Facilitates the conversion of fat into energy.[10]
  • Innoslim: A patented blend of ginseng[11] and astragalus,[12] claimed to stimulate fat-burning hormones and reduce carbohydrate absorption.
  • B vitamins: Support energy production[13] through metabolism.
  • Iodine: Influences the production of thyroid hormones,[14] needed for balancing metabolism and moods. 

Manufactured in Good Manufacturing Practice-approved facilities, PhenQ offers a money-back guarantee, multi-buy savings, and free US shipping. With its science-backed ingredients and comprehensive approach, PhenQ can be a valuable addition to weight loss strategies.


  • Tailored specifically to women.
  • It helps suppress appetite.
  • It may boost energy and alleviate fatigue.
  • Clinically proven ingredients.
  • GMP certified.
  • 90-day money-back guarantee.
  • Expensive.
  • Requires three doses daily.

Leanbean is a top-rated weight loss supplement designed to cater specifically to women. It promises weight loss, appetite suppression, and enhanced energy levels. Here’s how it fulfills these claims:

  • Glucomannan: This standout ingredient in Leanbean is a natural dietary fiber known for its ability to absorb water in the stomach. When consumed, Glucomannan[15] expands, giving a feeling of satiety. This helps reduce daily calorie intake by curbing overeating tendencies.
  • Vitamins B6 and B12: Combat tiredness and fatigue, which can be crucial for exercise efforts.
  • Choline: is a vital nutrient that promotes normal lipid metabolism,[16] contributing to the breakdown of fats.
  • Green coffee: Can reduce fat accumulation that contributes to lower belly fat and body weight.
  • Acai berry: A potent antioxidant that helps combat obesity-related metabolic disorders.[17]

Leanbean’s formula is designed with low stimulant ingredients, making it suitable for women looking for sustainable and science-backed results.

In terms of pricing, Leanbean offers various supply options. These include the Complete Bundle for $189.97, which lasts four months, a 60-day supply for $119.98, and a one-month supply starting at $59.99. 

Hourglass Fit

  • Women-centric supplement.
  • Clinically-backed ingredients.
  • Supports appetite suppression.
  • Reduces cravings.
  • Gluten, soy, allergen, and additives-free.
  • Stimulant-free.
  • Vegan-friendly.
  • Expensive.
  • Only accepts returns on sealed products.

Hourglass Fit weight loss pills emerge as an outstanding choice among fat burners for women who are sensitive to stimulants. This all-natural, vegan-friendly supplement excels at appetite suppression, energy enhancement, and metabolic support. Here’s how:

  • Appetite suppression: Hourglass Fit contains glucomannan and 5-Hydroxytryptophan for effective appetite control. Upon consumption, glucomannan absorbs water and swells in the stomach, creating a sense of fullness. Meanwhile, 5-HTP[18] has a remarkable impact on appetite as it elevates serotonin levels in the brain. This reduces cravings for sugary treats and increases cravings for proteins and fatty foods. The result is lower sugar and calorie intake, which aids in weight management.
  • Metabolism and energy boosters: The supplement includes a blend of essential vitamins such as B2, B6, and B12, along with chromium,[7] zinc, and the thermogenic duo of Capsimax and Bioperine. B vitamins support energy production, while zinc, facilitated by Bioperine,[19] reduces insulin resistance while increasing energy output.

Hourglass Fit offers different value bundles starting at $60. The brand accepts returns, provided the bottle is undamaged and sealed.


  • 100% natural. 
  • Helps burn fat.
  • Curbs appetite.
  • Boosts metabolism.
  • Suppresses appetite.
  • 100-day money-back guarantee.
  • Unsuitable for vegans or vegetarians.

Trimtone is an over-the-counter fat burner designed to boost pre-workout energy while promoting mental alertness during exercise sessions. The ingredients within this formula work together to deliver these benefits in the following ways:

  • Caffeine: As a natural thermogenic ingredient, caffeine enhances metabolism. It also acts as a central stimulant, promoting mental alertness to keep you sharp during workouts.
  • Green coffee: Green coffee is thought to improve insulin sensitivity, which, in turn, minimizes fat accumulation.[20]
  • Green tea: This ingredient may inhibit starch digestion and absorption, supporting weight loss by improving fat oxidation.[21]
  • Grains of paradise: Grains of paradise[22] activate brown adipose tissue, promoting higher energy expenditure. This energy boost is particularly beneficial during strenuous workouts and can contribute to faster fat burning.
  • Glucomannan: Glucomannan’s satiating effect helps curb cravings, further reinforcing calorie control by helping you feel full for longer.

With a retail price of just $69.99, Trimtone offers an affordable solution, making it an attractive option for those seeking to enhance their weight management journey with a pre-workout energy boost and appetite control.


  • Provides 24-hour fat loss.
  • Boosts metabolism.
  • Supports better energy production.
  • No prescription is needed.
  • Free worldwide shipping.
  • Costs substantially more than other brands.

Phen24 stands out as a unique fat-burning solution with a day and night formula, offering round-the-clock support for weight management. Unlike traditional fat burners, Phen24 comes in two bottles, each designed for specific times of the day.

Day Formula:

  • L-phenylalanine: This ingredient supports whole-body fat oxidation,[23] promoting weight loss.
  • Guarana: Guarana helps expand brown adipose tissue, potentially preventing obesity[24] and boosting calorie burning.
  • Cayenne: Cayenne contributes to fat burning through its thermogenic properties.
  • Ashwagandha: An adaptogen, Ashwagandha enhances cognitive functions,[25] memory, and reaction times.

Night Formula:

  • L-theanine: Recent animal studies[26] suggest L-theanine aids the conversion of white fat to brown fat, which is associated with heat generation and anti-obesity properties.
  • Griffonia: Griffonia or 5-HTP elevates serotonin levels, reducing appetite[18] and addressing issues like insomnia, anxiety, and depression.
  • Choline bitartrate: Choline bitartrate helps regulate the hunger hormone leptin,[27] reducing hunger pangs.
  • L-arginine: L-arginine may assist in managing disrupted metabolism in obesity[28] by potentially enhancing lipid and carbohydrate metabolism.

Priced at $84.99 per bottle, Phen24 stands as an effective 24-hour fat burner, making it one of the best options for women seeking consistent weight management support.

Capsiplex Trim

  • Facilitates fat oxidation.
  • Controls cravings.
  • Supports muscle development.
  • Boosts metabolism and fights fatigue.
  • Dairy, gluten, GMO, and soy-free.
  • Vegan-friendly.
  • Free shipping.
  • There’s a 5-bottle limit per order.
  • Contains patented ingredients.

Capsiplex Trim is an ideal fat burner for women looking to achieve lean muscle development while boosting energy and metabolism. These key ingredients make Capsiplex a top choice:

  • Capismax: A patented cayenne pepper extract renowned for its exceptional thermogenic properties, aiding[29] in fat and carbohydrate oxidation.
  • Green tea and green coffee extracts: These botanical extracts are potent metabolism boosters that contribute to calorie burning.
  • Innoslim: A blend of Panax notoginseng and Astragalus membranaceus, it supports weight loss efforts by improving insulin sensitivity.
  • Arginine: This nitric oxide precursor enhances[30] aerobic and anaerobic exercise performance, facilitating muscle growth and skeletal muscle performance.
  • Black pepper extract: Enhances the bioavailability of all other ingredients[31] in the formula, ensuring their effectiveness.
  • Minerals: Iodine, chromium, calcium, iron, and zinc provide comprehensive support for overall health and weight management.

Capsiplex Trim offers a vegan, gluten-free, dairy-free, and soy-free product suitable for various dietary preferences and restrictions. With prices starting at just $74.99 and discounts available on their website, Capsiplex Trim is an affordable solution for women looking to achieve their weight loss and fitness goals.


  • Helps control cravings and hunger pangs.
  • Boosts energy production.
  • Low-stimulant formula.
  • Dietitian-backed formula.
  • Costly.

Powher products are female fitness supplements made from clinically proven ingredients to deliver tangible results. Its core components include:

  • Glucomannan: This fiber promotes satiety without adding extra calories, aiding in appetite control.
  • Natural caffeine: Coffee arabica revs up metabolism and enhances workout performance.
  • Magnesium: Studies show that magnesium limits[32] the accumulation of adipose tissue, contributing to a leaner physique.
  • Selenium: Instrumental in promoting musculoskeletal function.[33]
  • Choline: Decreases body mass by supporting fat metabolism.[27]
  • Chromium picolinate: Contributes to glucose and insulin metabolism, helping regulate blood sugar levels and overall weight management.

Powher female fitness supplements are made from clinically-backed ingredients that have proven effectiveness, supporting optimal performance. The product line includes:

  • PRE-WORKOUT: Uses a low-stimulant system to improve exercise performance and enhance energy and endurance.
  • CUT: Incorporates an effective formula with a 3-gram daily dose of glucomannan, minerals, plant extracts, and natural stimulants.
  • MULTIVITAMIN: Tailored for women’s nutrient needs, this multivitamin provides essential minerals and vitamins.

Powher’s commitment to quality and effectiveness makes it a compelling choice for aging women looking to enhance their fitness and overall health.


  • Clinically proven formula.
  • Controls hunger and cravings.
  • Made from organic herbal ingredients.
  • Vegan-friendly.
  • Free deliveries.
  • Costly.

Zotrim is a renowned natural weight loss supplement with an herbal formula that’s backed by numerous clinical studies. It is highly regarded for outperforming prescription drugs in promoting weight loss.

Key Ingredients:

  • Yerba Maté: Aids appetite control[34] and reduces mental and physical fatigue.[35] Yerba Maté’s antioxidant-rich composition also enhances exercise energy, promoting fat burn.
  • Guarana: Packed with caffeine, guarana serves as a cognition nutrient,[36] boosting alertness.
  • Damiana: Offers an antidepressant and aphrodisiac effect, potentially assisting stress management.[37]
  • Caffeine: This ingredient energizes, invigorates, and enhances alertness and focus.
  • Vitamin B3 & B6: Essential B vitamins that support a healthy metabolism, reduce fatigue, and aid energy conversion from food.

Available at a retail price of $69.99 for one bottle, Zotrim offers an affordable and effective means to control appetite, curb cravings, and reduce calorie intake. Discounts are available when you purchase on the official site.

What Issues Do Women Over 50 Usually Face While Losing Weight?

Women over 50 encounter several challenges while trying to lose weight:

  • Metabolism naturally slows with age, making it harder to burn calories.
  • Hormonal changes during menopause transition lead to fat distribution changes.
  • Muscle mass decreases, instigating an increase in body weight.
  • Joint pain and reduced mobility limit physical activity, hindering exercise routines.
  • Emotional factors like stress and mood changes often affect eating habits.
  • Many women of this age are at high risk of specific medical conditions like osteoporosis, obesity, and diabetes that cause weight gain.
  • Dietary preferences and habits established over time are hard to change.

How Can Weight Loss Pills Help Women Over 50?

Weight loss pills help women over 50 shed excess pounds in several ways, depending on the specific ingredients. They work in the following ways:

Appetite Suppression

Research[38] shows that declining estrogen levels during and after menopause cause changes in hunger patterns. Ghrelin,[39] the hunger hormone, tends to increase during perimenopause, making you feel hungrier. On the flip side, leptin[40] production decreases. And since leptin is the satiety hormone, it triggers excessive eating as the brain cannot tell when it’s time to stop eating.

Many weight loss pills contain ingredients that help regulate appetite. Phentermine,[41] for instance, works on the central nervous system to suppress appetite.

Boosting Metabolism

Metabolism, the body’s natural calorie-burning process, tends to slow down with age, making it more challenging to shed unwanted pounds. Age-related metabolic changes[42] result from hormonal shifts, a decrease in muscle mass, and reduced physical activity. The lowered resting metabolic rate means the body burns fewer calories at rest, making creating the calorie deficit necessary for weight loss is more challenging.

Metabolism-boosting diet pills work by stimulating thermogenesis, which increases energy expenditure, revving up the metabolic rate. They contain thermogenic fat burner compounds that, when consumed, help the body burn more calories, even when at rest.

Most prescription weight loss drugs with thermogenic properties contain ingredients like:

  • Caffeine: Caffeine is a well-known metabolic booster. A recent systematic literature review by the International Journal of Sport Nutrition and Exercise Metabolism[43] established that caffeine stimulates the central nervous system, increasing heart rate and energy expenditure. You feel more alert and energized, making staying active and burning calories easier.
  • Green Tea Extract: Green tea contains compounds called catechins that have thermogenic properties. According to a 2021 study,[44] they increase metabolism, promoting the burning of fat for energy.
  • Capsaicin: Capsaicin is the compound responsible for the spiciness of chili peppers. It can raise the body’s temperature and increase calorie burning.
  • L-Carnitine: This amino acid plays a role in transporting fatty acids into the mitochondria, where they are burned for energy. It promotes fat metabolism, which supports weight loss.

Metabolism-boosting weight loss pills can vary from person to person, and they are most effective when combined with a balanced diet and regular physical activity.

Blocking Fat Storage

Another way in which a diet pill works is through fat-blocking mechanisms. As women age, hormonal changes and metabolic shifts trigger changes in how the body stores and utilizes dietary fats. Fat-blocking supplements aim to mitigate this effect by inhibiting the absorption of dietary fats in the digestive system.

These fat blockers work via:

Lipase Inhibition

Lipase is an enzyme that breaks down fats into forms that the body can absorb. Fat-blocking supplements often contain lipase inhibitors that reduce the enzyme’s activity. As a result, less fat is absorbed from the food you consume.

Fat Excretion

Instead of being absorbed, the undigested fats are excreted from the body in the stool. This leads to a reduction in calorie intake since the fat calories are not metabolized.

Reducing Caloric Intake

These weight loss pills help reduce the number of calories entering the bloodstream by blocking the absorption of dietary fats. This can result in a caloric deficit, which is crucial for weight loss. It’s especially beneficial for women over 50 who may need to be more mindful of their calorie intake due to a slowing metabolism.

Common ingredients found in fat-blocking weight loss pills[45] include:

  • Orlistat: This medication works by inhibiting pancreatic lipase, reducing the absorption of dietary fat. It’s available both as a prescription drug and in lower-dose, over-the-counter forms.
  • Chitosan: Derived from the shells of crustaceans, chitosan binds to fats in the digestive system, preventing their absorption.
  • Glucomannan: This dietary fiber expands in the stomach, creating a feeling of satiety, which reduces the consumption of high-fat foods.

Hormonal Regulation

Some diet pills support weight loss by addressing hormonal regulation. The transition through menopause is accompanied by changes in hormone levels that might cause you to pack on the pounds, particularly around the midsection. Fluctuations in hormones like estrogen, ghrelin, and leptin lead to increased appetite, disrupted metabolism, and difficulties managing weight.

Weight pills that influence hormonal regulation stabilize these imbalances, potentially making maintaining a calorie deficit necessary for weight loss easier. However, before using diet pills, especially those involving hormonal regulation, consulting with a healthcare professional is highly recommended. Hormonal change therapy should be addressed to align with an individual’s unique health profile and needs.

Nutritional Support

In addition to mechanisms like appetite suppression, metabolism boost, and hormonal regulation, most natural weight loss supplements provide nutritional support. Research[46] tells us that the ability to absorb certain nutrients can decrease with age due to factors like changing dietary preferences, increased appetite, or specific dietary restrictions.

When taken, these pills provide essential vitamins, minerals, and nutrients that might be lacking in the diets of older individuals.

Diet pills that contain nutrients support weight loss in women in this age group by:

  • Filling nutritional gaps.
  • Enhancing energy levels.
  • Enhancing metabolism.
  • Boosting bone health.
  • Supporting overall wellness.
  • Providing support for hair and skin.

Note: Not all weight loss pills offer nutritional support, and the specific nutrients and their dosages can vary widely between products. This is why you must carefully read product labels and consult with a healthcare professional to ensure that the chosen supplement aligns with your health needs and dietary requirements.

Those with nutritional value are intended to complement a balanced diet, not to replace it. They should be used as part of a broader strategy for weight management that includes healthy eating and regular exercise.

What About Water Pills?

While not a sustainable or recommended method, diuretics have been shown to cause temporary water loss, which leads to a reduction in body weight. This medication is often recommended for managing and treating edematous and other non-edematous conditions like high blood pressure, heart failure, and liver disease.

Also known as water pills, diuretics work by: 

  • Increasing urine production: Diuretic supplements prompt the kidneys to excrete excess sodium and water from the body through urination.
  • Reducing water retention: By decreasing the accumulation of fluids in the body’s tissues, diuretics prompt water weight loss.

However, note that this weight loss is due to fluid loss rather than fat loss. As soon as you stop taking water pills, your body will regain the fluid weight.

In addition, water pills come with side effects, including dehydration, dizziness, lightheadedness, and muscle cramps. Sometimes, water pills can also lead to serious health problems, such as electrolyte imbalances and kidney damage.

A 2023 comparative study[47] on the hydration status in older adults affirms that dehydration increases with age due to changes in the water and sodium balance. There’s a 5%-10% decrease in total body water.[48] When you’re dehydrated, your body tries to restore its balance by retaining water. Using a diuretic may hinder these efforts, further aggravating the dehydrative state.

There’s also a reported risk of abuse by athletes looking for a quick fix or people with eating disorders like bulimia nervosa.

If you’re considering taking a weight loss supplement, do your research and consult a medical professional first. They can help you choose the right supplement for your individual needs and make sure that it’s safe for you to take.

Tips On How To Get The Best Results

If you’re considering taking diet supplements as part of your weight loss journey, check out these tips to get the best results:

  • Consult a healthcare professional. 
  • Choose the right supplement.
  • Follow dosage instructions.
  • Use alongside a healthy diet.
  • Get regular exercise.
  • Stay hydrated.
  • Sleep well.
  • Manage stress.
  • Monitor progress.
  • Avoid fad diets.


Weight loss supplements can be valuable when used with a balanced diet, regular exercise, and a commitment to healthy lifestyle choices. And finding the right diet supplement can make a significant difference, particularly for women over 50.

The eight best weight loss supplements highlighted in this article offer a range of benefits, from appetite suppression to metabolism enhancers and muscle builders, to support weight loss in 2023. Whether you opt for PhenQ or Zotrim, ensure you select the right supplement, consult with a healthcare professional, and adhere to recommended dosages.

All in all, remember there is no magic pill, and sustainable weight loss for women over 50 requires dedication and a holistic approach. Dedication and perseverance are your most potent allies on this journey to a healthier you.

Frequently Asked Questions

What is the best fat burner for women over 50?

The best fat burner for women over 50 varies depending on individual needs and goals.

What should a 55-year-old woman eat to lose weight?

A 55-year-old woman should eat a healthy diet that is low in processed foods and high in fruits, vegetables, lean proteins, and whole grains.

What is the best supplement for women’s weight loss?

The best supplements for women trying to lose weight contain ingredients like phentermine, glucomannan, caffeine, capsaicin, conjugated linoleic acid, garcinia cambogia, green tea extract, fiber, protein powder, and omega-3 fatty acids.

What is the best weight loss pill for women over 50?

Weight loss supplements that may be effective for women over 50 include orlistat and phentermine. It is best to talk to your doctor before taking any weight loss pill, especially if you have any underlying health conditions.

How can a woman over 50 lose weight fast?

The best way for a woman over 50 to lose weight involves making changes to her lifestyle. This includes eating a balanced diet, working out regularly, and quitting habits like smoking. However, fast weight loss is not typically recommended.

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Mitchelle Morgan is a health and wellness writer with over 10 years of experience. She holds a Master's in Communication. Her mission is to provide readers with information that helps them live a better lifestyle. All… See More

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