6 Best Appetite Suppressants That Help Control Your Hunger In 2024

mitchelle morgan

Reviewed by Sevginur Akdas, PhD
best appetite suppressant
The best appetite suppressants in weight loss. Photo: Team Design

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Starting your weight loss journey involves the pivotal question: “How do you lose weight?

Many remedies to help you lose weight exist, but today’s focus is on appetite control using suppressants.

This review will highlight six of the best appetite suppressants for weight loss. We’ll compare the brand’s claims to science. Additionally, we’ll explore natural weight loss remedies, including herbal extracts, prescription, and over-the-counter choices.

We aim to offer you the facts to ensure you select only the best weight loss supplements. Use this guide to find the best appetite suppressant and fat burner for healthy weight loss.

Best Appetite Suppressant Pills In 2024

  • PhenQ – Editor’s Choice
  • Leanbean – Best Women’s Appetite Suppressant
  • Instant Knockout – Best Appetite Suppressant For Athletes
  • PhenGold – Best Vegan Appetite Suppressant
  • Zotrim – Best Herbal Appetite Suppressant
  • Trimtone – Best Over-The-Counter Appetite Suppressant

Best Appetite Suppressant Pills In 2024


  • May boost metabolism.
  • Non-GMO ingredients.
  • May improve brain health.
  • Costly.
  • Some ingredients need more recent research.

PhenGold claims they offer decreased appetite and enhanced mental and metabolic health. The brand also suggests it optimizes energy expenditure, reducing fat accumulation.

Here is how PhenGold supports weight loss:

PhenGold is one of the popular weight loss supplements due to its versatile formula.

The supplement is vegan and free of GMO, soy, gluten, and dairy. It’s also natural with zero additives or preservatives.

It’s ideal for men and women over 18 years old, and they recommend it for athletes on a fitness plateau. Still, ensure you see a doctor for a full assessment before use.


  • Natural herbal formula.
  • Well-researched ingredient list.
  • Contains neuroprotective ingredients.
  • Expensive.
  • Outdated research.

Zotrim is an herbal weight loss formula that curbs appetite and reduces calorie intake.

Zotrim’s ingredients at $69.99 claim to offer the following weight loss benefits:

One fact about this brand is that it’s among the few with an actual study to test its efficiency. The older 2007 research highlights it promotes satiety with weight loss effects. There is a need for a recent study to confirm these results, but there isn’t one available yet.

It’s also best for people battling fatigue while on weight loss journeys.


  • May boost mental health.
  • May stimulate thermogenesis.
  • Free worldwide shipping.
  • One capsule a day.
  • Costly.

Trimtone boasts of being one of the best over-the-counter weight loss pills for women. It claims to suppress appetite, boost mental clarity, and provide ample energy for your workouts.

At the retail price of $69.99, the brand claims the ingredients offer:

Unlike most non-prescribed diet pills, Trimtone is a one-capsule formula. One is enough for the day.

Pregnant and lactating women should refrain from using this supplement. It contains stimulants that may affect both the mother and child. It is also not vegan because it contains gelatin.

Do Appetite Suppressants Actually Work?

Curious about the efficacy of appetite suppressants?

Here is the science behind three types of weight loss aids and how they work.

Natural Extracts And Other Botanical Supplements

Natural appetite suppressants work by:

Modulating Hunger Hormones

Natural plant extracts in certain foods may suppress feelings of appetite.[43] These extracts interact with the hunger hormones ghrelin and leptin.[44]

The stomach lining produces ghrelin, stimulating the brain to signal hunger. When your tummy is empty, ghrelin levels increase, and you crave food. Ginger regulates ghrelin, reduces hunger, and promotes satiety.[45]

Fat cells produce leptin. Leptin aids energy balancing by signaling the brain about the body’s fat stores. When you have an increased number of fat cells, leptin levels rise. This signals your body has enough energy stores, thus less appetite and increased energy expenditure.

Ginseng regulates leptin levels,[46] which facilitates less easting due to satiety. Green tea also increases leptin levels,[47] promoting appetite control.

Increasing Fiber Intake

Dietary fiber may slow down nutrient absorption and digestion.[48] This means there may be less carbohydrate and fat absorption in the gut, promoting weight loss. 

Stimulating And Modifying The Stomach Content

Glucomannan’s absorbent nature expands to fill the tummy. This size increase signals the body that the stomach is full.

Psyllium husk also offers the same satiating effects.[49] Other fiber sources are guar gum,[50] fenugreek seeds,[51] and chicory root.[52]

Prescription Medications

There are several prescribed best appetite suppressant pills with studies to support their claims. Examples are:

Please note that there are strict instructions when using these prescription appetite suppressants. Some general rules are:

  • Follow your doctor’s instructions.
  • Never skip dosages or double them.

Over-The-Counter Weight Loss Pills

Over-the-counter weight loss pills are also a hit in this industry.

They claim to curb appetite in several ways depending on the ingredients. Some are thermogenic, others stimulate satiety signals, while others fill the stomach.

Despite the marketing, exercise caution. Possible downsides encompass allergic reactions, physical discomfort, and adverse drug interactions. 

Some, like those containing creatine,[57] may also affect water retention, leading to temporary weight gain. This may have you seeking more supplements or remedies to lose water weight.

So, seek medical attention if you notice any physical discomfort like abdominal or chest pain. Active medical monitoring could save you from kidney problems later.

Some measures to avoid health implications while on OTC appetite suppressants are:

  • Read the product labels.
  • Check for third-party testing.
  • Check for product certifications.
  • Vet the ingredients, their quantities, and efficiency through research.
  • Read the client reviews for real-life evidence. For example, reading PhenQ’s client reviews may help you better decide if the diet pills fit your needs.

Things To Note Before Using Any Appetite Suppressant

Suppose you want to use the best appetite suppressant for weight loss, consider the following:

Consult A Healthcare Professional

Start your weight loss journey with a doctor’s visit and a trip to see a registered dietitian. Doctors will provide insights into potential risks and benefits, while RDs help you develop a personalized weight loss plan.

Be Aware Of Potential Side Effects

All manufactured medications, including appetite suppressants, pose potential side effects. The effects vary in severity based on your health status, the ingredient list, and dosage compliance.

Some common effects include, but are not limited to, constipation, high blood pressure, or increased heart rate. You may also experience jitters and insomnia from consuming stimulants like caffeine.

Understanding and discussing these and other effects with your doctor is crucial.

Consider Lifestyle Changes

Solely relying on appetite suppressants is ineffective and dangerous. Appetite suppressants complement, not replace, a holistic approach to weight management. Sustainable weight loss includes a healthy diet, regular exercise, and enough sleep.

Following these lifestyle changes alongside suppressants enhances your chances of success.

Be Cautious Of Unrealistic Claims

Brands often exaggerate their marketing campaigns. They may claim unrealistic promises of rapid, effortless weight loss. Weight loss is achievable, but healthy weight management needs commitment and time. So, set and maintain realistic expectations, and avoid weight loss diet pills that sound too good to be true.

Be Aware Of Potential Interactions

Appetite suppressants may interact with existing medications or supplements. These interactions may compromise the supplement’s effectiveness.

To avoid this, tell your doctor about your complete regimen to prevent potential clashes. This transparency ensures your safety.

Don’t Substitute Proper Medical Care

Appetite suppressants are not standalone solutions. If you’re grappling with weight issues or health concerns, seek comprehensive medical care. Avoid using suppressants as substitutes for diagnosis, treatment, or disease management.

Do Not Share Weight Loss Pills Or Use Unguided

As tempting as it may be, it’s dangerous to share appetite-suppressing supplements. Sharing may lead to improper dosages and may also encourage misuse. It also heightens the risks of adverse reactions and medical interactions. Without guidance, you overlook addictions, dependency, and side effects severity. 

Natural Ways To Suppress Your Appetite

Appetite is diet-centric, and here are some natural modifications to control your appetite:

  • Boost your satiety levels by consuming lean protein-rich foods like chicken, fish, beans, and tofu. Aim for at least 0.80 grams of protein per every kg body weight daily[58] to prevent deficiency, although recent research indicates 1.2-1.5g/kg is more appropriate.[59] Energy percentage specifies the range of protein intake as a percentage of total calorie intake; high protein may be up to 35% of energy intake.
  • Add whole grains, fruits, vegetables, and legumes to boost your fiber intake. Whole grains slow digestion and promote fullness, unlike refined grains. Increasing your dietary fiber intake by 3.7 grams per day over the usual intake of ≥ 20 grams[60] may lead to a 1.4-kilogram greater weight loss over six months. Ensure you hydrate to promote regular bowel movements.
  • Be mindful when you eat food. Eat slowly and chew thoroughly. Slow eating may increase feelings of fullness[61] and reduce overindulgence.
  • Focus on low-calorie, high-volume foods. These are foods like vegetables and fruits. They fill up the plate but have fewer calories. Add thermogenic spices such as chili peppers, cayenne pepper, and ginger to stimulate metabolism.
  • The caffeine and catechins of herbal teas such as green tea also promote natural appetite suppression. Coffee may also help keep cravings in check.
  • Sleep is essential in many ways. First, sleep is a natural antidepressant, helping you beat the urge of emotional eating. Second, it impacts hormonal rhythms.[62] This means that sleep deprivation may affect the regulation of hunger hormones. This way, it may implicate your weight loss goals. Adults should aim to get seven to nine hours[63] of quality sleep.
  • Manage stress through meditation and yoga to curb stress-induced cravings.
  • Try natural supplements after ample research and consultation from your doctor.

All these natural remedies are effective, but always consult a healthcare professional before use. 


Losing weight through appetite suppression is achievable, but what’s the best appetite suppressant supplement?

It depends. Picking the best depends on your health, weight loss goals, and the doctor’s assessment.

Above, we have six brands promising to aid weight loss through appetite suppression. Thanks to their formulas, you may experience better mental, metabolic, and energy health. Still, note that everyone’s experience using these products is unique.

Health professionals can help you answer questions like “How long does it take to lose weight?” So, consult one if you have questions.

If you have any underlying health conditions, prioritize getting medical advice, too. Also, know the potential health consequences. 

Sure, these supplements may work, but don’t rely solely on them. Also, never underestimate natural appetite suppressant supplements and lifestyle modifications. It is possible to lose weight by running on a treadmill while consuming a healthy, balanced diet with supplementation. 

Frequently Asked Questions

What is the best supplement to stop hunger?

Glucomannan, a water-soluble fiber, is a top choice. It swells in your stomach, inducing fullness and reducing hunger, making it an effective natural supplement.

What naturally curbs your appetite?

Protein-rich foods like chicken and beans, healthy fats from nuts, and fiber-loaded options like whole grains and veggies. These natural choices promote fullness and curb appetite.

What’s a good weight loss pill that works?

Prescription medication, such as Phentermine-Topiramate, has proven efficacy in weight loss. However, consult a healthcare professional before considering any weight loss pills.

How can I permanently reduce my appetite?

Focus on lifestyle changes-prioritize sleep, manage stress, stay active, and adopt a diet rich in protein, healthy fats, and fiber. These habits can contribute to long-term appetite control.

What can stop you from eating?

Natural supplements like glucomannan or prescription medications like Phentermine – Topiramate can help control eating habits. Always consult with a healthcare professional for personalized advice.

Are there any over-the-counter appetite suppressants that work?

Some over-the-counter options may help, but their effectiveness varies. Green tea extract, coffee, and spices like cayenne pepper can offer mild appetite suppression. Always check with a healthcare professional before trying.

Can supplements like green tea extract or coffee have side effects?

Yes, while generally safe, excessive caffeine intake from green tea or coffee can lead to side effects like anxiety and insomnia. Moderation is essential, and individual reactions may vary.

Is there a natural appetite suppressant with minimal side effects?

Yes, fiber-rich foods like glucomannan have minimal side effects. However, starting with a low dose and gradually increasing is essential to avoid digestive discomfort. 

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Mitchelle Morgan is a health and wellness writer with over 10 years of experience. She holds a Master's in Communication. Her mission is to provide readers with information that helps them live a better lifestyle. All… See More