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Best CBD Cream For Arthritis Pain: Top 7 Choices In 2024

Teresa Mboci

Reviewed by Dr. Drew Sutton, MD
best cbd cream for arthritis pain
Treatments for arthritis can benefit from CBD pain cream. Photo: Team Design

Each article is created without any external influence. When you use our provided links to buy products, we receive a commission as an affiliate. To understand how we generate revenue, please read our advertising disclaimer.

As everyone knows, physical suffering is unbearable. Pain of a severe or chronic nature can make even the most basic of duties difficult, if not impossible. Opioid drugs[1] with significant side effects are commonly used to treat chronic pain.

The risks of these drugs typically outweigh any advantages they may have. CBD pain cream, a novel, non-addictive pain treatment, has recently gained widespread attention in the medical community. Topical CBD cream might help your body in several ways. Treatments for arthritis and acne can benefit from their ability to decrease sebum production in the body.

In addition, it performs an excellent job of reducing the inflammation, itching, and swelling that can occur as a result of physical activity or other skin disorders. Because the benefits of CBD are still being researched, it is best to discuss its use with a doctor before beginning treatment. In this review, we look at the 7 best CBD creams for arthritis pain. 

7 Best CBD Cream For Arthritis Pain 2024

Does CBD Work For Pain?

The precise mechanism by which CBD exerts its effects is unknown. Experts believe it may help with common issues by interacting with your body’s endocannabinoid system (ECS).

According to research,[2] the ECS promotes homeostasis by facilitating cell communication. For example, ECS can help alleviate pain, inflammation, stress, and other symptoms due to accidents or illness. 

Endocannabinoids, which are molecules produced by your body, can activate the ECS. CBD and THC are two types of cannabinoids that, like endocannabinoids, have the ability to change how your brain and body respond to stimuli.

7 Best CBD Creams For Arthritis In 2024: Products & More

CBDfx Muscle and Joint Cream

CBDfx Muscle and Joint Cream

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25% Off Exclusive Coupon: HEALTHCANAL

  • Multiple ways of delivery 
  • Certificate of analysis available
  • 60-day satisfaction guarantee
  • Timeframes of delivery are not guaranteed

CBDfx now provides a variety of topical CBD products from full-spectrum oils to broad-spectrum oils to CBD isolate, all derived from non-GMO, organically cultivated hemp. Pain management could be lessened by using CBDfx CBD Cream. In addition to broad-spectrum CBD,[3] this hemp cream contains soothing menthol and white willow bark, which may help reduce minor aches. Caffeine, to which some people may be particularly sensitive, is also included. The light, pleasant aroma of the cream lingers on the skin after application, and it absorbs quickly without leaving any oily residue.

CBDistillery CBD Warming Cream

CBDistillery CBD Warming Cream

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25% Off Coupon: HEALTHCANAL25

  • Gentle and oil-free
  • 60-day money-back guarantee
  • Contains anti-inflammatory essential oils and botanical extracts, such as rosemary
  • Costly compared to other options

CBD Warming Cream from CBDistillery will appeal to those who find relief from arthritis pain through a warming sensation. With only 2 milligrams in every pump, you may take advantage of CBD whenever you need it. It also induces a subtle yet soothing warming sensation on the skin, which can be quite beneficial for relieving pain in some areas. This cream is made using domestically grown, non-GMO hemp.

Cornbread Hemp CBD Lotion, Menthol Formula  

  • Several hundred positive reviews from satisfied clients
  • Pure CBD oil and other full-spectrum CBD products
  • A wide selection of products
  • Most of our goods are certified organic by the USDA
  • All products are full-spectrum, thus they won’t work for THC-averse users

If you want an all-natural option, the Cornbread Hemp CBD Lotion is an excellent choice. This USDA-certified organic lotion for arthritis pain contains a variety of organic ingredients, including organic menthol, organic hemp extract, and distilled water. According to the manufacturer, each jar contains 20 milligrams of THC and approximately 60 individual servings containing 8 milligrams of CBD. However, according to the producer, the item can be used as liberally as the buyer sees fit.

Aspen Green Muscle Relief Cooling Cream

Aspen Green Muscle Relief Cooling Cream

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20% Off With Code: HEALTHCANAL

  • Contains a THC content of less than 0.3%
  • Void of toxins
  • Approved as an organic product by the USDA
  • Takes a long time (up to 2 weeks) for results to show

Try out Aspen Green’s Muscle Ease Cooling Cream for some much-needed relief from achy muscles and joints. Aspen Green’s soothing cream contains organic menthol, organic tea tree oil, and organic arnica extract, which combine synergistically to reduce pain and hasten recovery. You should rub the cream into your neck and shoulders, as directed.

Charlotte’s Web Hemp-Infused Cream with CBD  

Charlotte’s Web CBD Cream

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20% Off Coupon: HEALTHCANAL

  • Vegan-friendly
  • Excellent for hypersensitive skin
  • Naturally gluten-free, paraben-free, and non-GMO 
  • Size options are extremely limited

If you have sensitive skin or allergies, try Charlotte’s Web CBD Hemp Infused Cream. Charlotte’s Web CBD Cream consists of full-spectrum hemp extract, oat extract, sea buckthorn oil, and coconut oil. The manufacturer asserts that their product can be used by anyone with sensitive skin because of the way its ingredients work together to relieve dry, itchy skin and encourage the skin’s natural regeneration process.

Medterra Pain Relief Cream

Medterra Pain Relief Cream

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15% Off Coupon: HEALTHCANAL

  • Validated by the United States Hemp Authority
  • Excellent customer feedback
  • Reasonably priced
  • Does not have 3rd-party certification

The Medterra Pain Relief Cream is difficult to beat for general use. Medterra’s CBD Quick Cooling Cream contains CBD, menthol, and arnica, which work together to quickly and effectively relieve pain and inflammation. The CBD component in the topical cream activates the skin’s CB2 receptors. These receptors are part of the body’s endocannabinoid system and respond to cannabidiol by reducing inflammation, and pain, and promoting healing.

Receptra CBD Serious Relief Plus Arnica Cream

Receptra CBD Serious Relief Plus Arnica Cream

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15% Off Coupon: HEALTHCANAL

  • Competitive rates
  • Guaranteed refunds
  • Nothing artificial is used in the production of these goods
  • There is a chance that THC is present in some items

Receptra CBD Serious Relief Plus Arnica Cream’s organic and natural elements are extremely beneficial for inflamed areas of your body, allowing for quick recovery and relief from daily stressors. The potent combination of natural CBD hemp, arnica, and jojoba in this cream relieves swelling and inflammation. Regardless of one’s age, pain and suffering are natural byproducts of a full and active existence. Your relief and recovery must meet you at the bar you’ve set for yourself.

What Is CBD Cream?

In recent years, the therapeutic and medical potential of the cannabis plant has come into focus. CBD cream, in contrast to CBD oils and edibles, is designed solely for topical use.[4] This shows that they may be effective in reducing certain types of discomfort and treating skin problems. CBD cream is popular among athletes because it is included in a variety of treatments designed to relieve aching muscles and joints. Yet, anyone who has ever experienced muscle pain or injury, arthritic pain, or any other inflammatory condition would benefit from utilizing CBD cream.

How Does CBD Help With Pain?

You may be unaware that your body naturally produces cannabinoids called endocannabinoids. To maintain homeostasis or internal balance, your endocannabinoid system regulates and restores several biological activities. In the case of overheating, for example, the endocannabinoid system sends a signal to the body to produce perspiration in order to cool down.

Animal studies show that CBD oil has an effect on the endocannabinoid system.[5] Cannabinoid receptors are abundant throughout the nervous system, including the brain. Because of their proximity to the nervous system, receptors aid in the transmission of pain signals. According to scientific studies, CBD oil or cream applied topically can improve the body’s natural ability to control pain by increasing the production of endocannabinoids.

Evidence[6] suggests that CBD can lessen the severity of chronic neuropathic pain, enhance sleep, and lessen the emotional toll that pain can take. Animal studies have shown that CBD can reduce inflammation and pain associated with arthritis.

Benefits Of CBD Cream For Arthritis

There are numerous benefits to applying CBD topically, some of which are described below:

Treatment Of Chronic Skin Diseases

According to the findings[4] in 2020, CBD is an effective and safe treatment for people suffering from chronic skin disorders such as psoriasis and atopic dermatitis, as well as the scars that result from these conditions.

Reduce Arthritis Pain

In a 2017 study,[7] researchers found out that CBD therapy at the site of arthritic inflammation in rats significantly lessened the severity of the condition.

Soothe Muscle Pain

People’s muscles and joints may pain after they’ve completed a chore or workout that was particularly challenging. Research[8] has demonstrated that applying CBD lotion can assist the body in recovering from the aches and pains that are associated with daily life.

Wound Care

According to a case[9] report published in the Journal of Pain and Symptom Management in 2017, CBD and THC can provide relief from pain and other symptoms associated with malignant wounds when applied topically. 


ECS receptors in the skin are involved in both pain and inflammation, and an in vitro study showed that CBD binds to these receptors and reduces their sensitivity.

Potential Side Effects

CBD has some mild adverse effects, including dry mouth, diarrhea, fatigue, and lethargy, but its long-term effects remain unknown. Due to the possibility of CBD amplifying the effects of blood thinners such as Warfarin, caution is suggested while combining the two medications. Cannabidiol (CBD) may have a small blood-thinning effect, according to some data; however, additional research[10] is required to validate this. The FDA discourages the use of CBD and similar products during pregnancy and nursing. It has been established that high levels of CBD in the mother’s system are connected with birth abnormalities and are transmitted to the newborn through breast milk.

How To Choose The Best CBD Cream For Pain?

Ingredients Used

Toxic levels of additional chemicals found in some CBD brands should be avoided. Look for CBD topicals that only contain natural ingredients.

Type Of Pain

Using too much CBD cream on the painful area is not recommended due to the possibility of an unpleasant reaction. CBD cream should also not be applied directly to sensitive skin. Instead, dab it on a cotton ball or piece of tissue paper before applying it to your skin.

Time Taken To See Results

If you require quick results, you may want to choose a CBD cream that contains only pure CBD isolate.

Type Of CBD Used

The type of CBD in your cream may influence how well it works. Several competitors’ products only contain CBD isolate.[11] Pure CBD isolate contains no psychoactive cannabinoids. Full-spectrum CBD, on the other hand, contains both THC and the other cannabinoids (including CBD) found in hemp.

Amount Of CBD

This is the most important consideration while searching for a CBD cream to relieve pain. Consult the manufacturer of your cream to determine how much CBD it contains. This information should be disclosed on their website or packaging.

THC Quantities

CBD creams contain so little THC that you will not get high from them. If you enjoy the sedative effects of THC, a CBD cream with a higher THC concentration may be preferable.


Cannabidiol lotions are more expensive than over-the-counter alternatives such as ibuprofen, but they still provide significant savings. If you’re looking for something that works quickly without breaking the bank, look no further than the top 7 best cannabidiol creams for pain.

How To Use CBD Arthritis Cream?

There is an extensive variety of CBD products available. The label and packaging of a product should provide the frequency and dosage recommendations for consumers, as well as any special preparation or application instructions. Various parameters, including body weight and effectiveness, will affect the appropriate dose. The experts advise first-time CBD users to start with the smallest effective dosage and increase only when necessary.

The analgesic effects of CBD may affect both the CNS (which receives pain signals from the body and transmits them to the brain) and the source of pain (such as your finger joints). One of the reasons CBD has therapeutic potential for arthritic pain is that it can suppress this response.

Another benefit of CBD is that it lessens inflammation. Animal research[12] has indicated that CBD may help reduce pain and inflammation, however, comprehensive human trials are yet to support these results. 

Final Thought

There have been encouraging results from using topical CBD creams to relieve arthritis pain. If it has the anticipated impact on the immune system and brain receptors, researchers are confident that it would lessen inflammation and discomfort. 

Human trials proving the value of CBD product is rare because of cannabis-related restrictions. The motivation to examine the substance grows as it becomes more legal, and early results have been promising.

It could take some trial and error to figure out which CBD creams or other topicals are best for you because everyone’s ECS is unique. It’s important to find a reliable manufacturer and remain with them if you want consistently high quality.

Frequently Asked Questions

What is CBD cream for arthritis pain?

Cannabidiol (CBD) cream is a topical medication that is applied to the skin to relieve arthritic pain.

What makes CBD cream effective for arthritic discomfort?

CBD cream reduces inflammation and discomfort by interacting with the endocannabinoid system in the body.

Is it legal to purchase CBD cream in the USA?

In the United States, CBD topical creams with less than 0.3% THC are considered legal.

What are the benefits of using CBD cream for arthritis pain?

The pain, swelling, and stiffness that accompany arthritis can be alleviated with the use of CBD cream.

Does taking CBD cream for arthritis pain come with any negative effects?

The moderate side effects of CBD cream are uncommon and include dry mouth, disorientation, and lethargy.

How do I choose the best CBD cream for arthritic pain?

Try to find CBD creams that have both high-quality organic CBD and other natural components like essential oils or menthol.

How often do you recommend applying the CBD cream to relieve arthritic pain?

This really depends on how bad your discomfort is.

How do I store CBD cream?

CBD cream should be kept out of direct sunlight in a cool, dry place.

+ 12 Sources

EHproject has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We work mostly with peer-reviewed studies to ensure accurate information. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

  1. Khalid, N. and Singh, A. (2022). Cannabis Versus Opioids For Pain. [online] Nih.gov. Available at: https://www.ncbi.nlm.nih.gov/books/NBK573080/.
  2. Mlost, J., Bryk, M. and Starowicz, K. (2020). Cannabidiol for Pain Treatment: Focus on Pharmacology and Mechanism of Action. International Journal of Molecular Sciences, [online] 21(22), p.8870. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700528/.
  3. Vigil, J.M., Montera, M.A., Pentkowski, N.S., Diviant, J.P., Orozco, J., Ortiz, A.L., Rael, L.J. and Westlund, K.N. (2020). The Therapeutic Effectiveness of Full Spectrum Hemp Oil Using a Chronic Neuropathic Pain Model. Life, [online] 10(5), p.69. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281216/.
  4. Baswan, S.M., Klosner, A.E., Glynn, K., Rajgopal, A., Malik, K., Yim, S. and Stern, N. (2020). Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders. Clinical, Cosmetic and Investigational Dermatology, [online] Volume 13, pp.927–942. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736837/.
  5. Silver, R.J. (2019). The Endocannabinoid System of Animals. Animals, [online] 9(9), p.686. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770351/.
  6. Xiong, W., Cui, T., Cheng, K., Yang, F., Chen, S.-R., Willenbring, D., Guan, Y., Pan, H.-L., Ren, K., Xu, Y. and Zhang, L. (2012). Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors. Journal of Experimental Medicine, [online] 209(6), pp.1121–1134. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371734/.
  7. Philpott, H.T., O’Brien, M. and McDougall, J.J. (2017). Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis. Pain, [online] 158(12), pp.2442–2451. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690292/.
  8. Frane, N., Stapleton, E., Iturriaga, C., Ganz, M., Rasquinha, V. and Duarte, R. (2022). Cannabidiol as a treatment for arthritis and joint pain: an exploratory cross-sectional study. Journal of Cannabis Research, [online] 4(1). Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400326/.
  9. Maida, V. (2017). Medical Cannabis in the Palliation of Malignant Wounds—A Case Report. Journal of Pain and Symptom Management, [online] 53(1), pp.e4–e6. doi:https://doi.org/10.1016/j.jpainsymman.2016.09.003.
  10. Lowin, T., Tingting, R., Zurmahr, J., Classen, T., Schneider, M. and Pongratz, G. (2020). Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts. Cell Death & Disease, [online] 11(8). Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463000/#:~:text=Side%20effects%20of%20CBD%20in,other%20therapeutic%20compounds14%2C15.
  11. Cocetta, V., Governa, P., Borgonetti, V., Tinazzi, M., Peron, G., Catanzaro, D., Berretta, M., Biagi, M., Manetti, F., Dall’Acqua, S. and Montopoli, M. (2021). Cannabidiol Isolated From Cannabis sativa L. Protects Intestinal Barrier From In Vitro Inflammation and Oxidative Stress. Frontiers in Pharmacology, [online] 12. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115937/.
  12. Gugliandolo, E., Licata, P., Peritore, A.F., Siracusa, R., D’Amico, R., Cordaro, M., Fusco, R., Impellizzeri, D., Di Paola, R., Cuzzocrea, S., Crupi, R. and Interlandi, C.D. (2021). Effect of Cannabidiol (CBD) on Canine Inflammatory Response: An Ex Vivo Study on LPS Stimulated Whole Blood. Veterinary Sciences, [online] 8(9), p.185. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473042/.


A dedicated pediatric nurse with a passion for nutrition and wellness, Teresa has made it her mission to empower families with the tools and knowledge they need to promote optimal health and well-being in their children.… See More